Alice Winifred O’Connor was born on June 11, 1886 in Lawrence, Massachusetts to John P. and Susanna (Brassill) O'Connor. Both of Miss O'Connor's parents were Irish immigrants. John was a police officer in the Lawrence Police Department and Susanna was a housewife. Alice O'Connor was the youngest of four daughters, her sisters being named Mary, Susanna, and Eleanor.
O'Connor was raised in Lawrence, graduating from the Oliver Grammar School in 1899 and the Lawrence High School in 1903. She was the valedictorian of her high school class. She continued her education at the Lowell Normal School as well as the Lawrence Training School for Teachers, graduating from the latter in 1906.
Miss O'Connor spent her life meeting the needs of the immigrants throughout the state of Massachusetts. Her career spanned several fields, including education, social work, and law. She also participated in several important committees and organizations, including the National Citizenship Program and the International Institute. She lived her in her family's home at 19 Logan Street until her death in 1966.